| 纪雪莹,张艳.上海市社区老年人肌少症患病情况及相关因素分析[J].老年医学与保健,2025,31(6):1474-1478+1483 |
| 上海市社区老年人肌少症患病情况及相关因素分析 |
| Prevalence of sarcopenia among elderly community residents in Shanghai and analysis of its related factors |
| |
| DOI：10.3969/j.issn.1008-8296.2025.06.014 |
| 中文关键词: 老年 肌少症 患病率 危险因素 衰弱 |
| 英文关键词: elderly sarcopenia prevalence risk factor frailty |
| 基金项目:上海市东方英才领军计划A类(2022);; 临床医学研究中心重点学科老年衰弱症(LCXZ2202);; 2023年上海市卫生健康系统重点扶持学科(2023ZDFC0402);; 中国青年创业就业基金(第八期11号);; 上海市卫生健康委员会科研项目(20254Y0082) |
|
| 摘要点击次数: 624 |
| 全文下载次数: 255 |
| 中文摘要: |
| 目的 探索上海市社区老年人肌少症的患病情况及影响因素。方法 2018年7月至2020年7月，随机抽样法募集上海市周家桥街道、天山路街道和九亭镇1 713名老年受试者。收集受试者的人口学资料、人体学指标和实验室指标。将受试者分为肌少症组（n=354）和非肌少症组（n=1 359），分析肌少症的影响因素。结果 社区老年人肌少症患病率为20.67%（354/1 713）。与非肌少症组相比，肌少症组年龄较大，体质量指数（BMI）、体脂率（BFR）、腰围、臀围、腰臀比、臂中围和小腿围较低; Fried衰弱表型（FFP）得分较高，微型营养评价得分较低;白细胞介素（IL）-17水平较低，总胆固醇、IL-6、肿瘤坏死因子-α及半乳凝集素（galectin）-3水平较高（P<0.05）。多元Logistic回归显示，年龄、BMI<18.5 kg/m2、FFP衰弱前期、FFP衰弱、总胆固醇和galectin-3水平升高是社区老年人肌少症的危险因素（P<0.05）。锻炼、BMI≥24.0 kg/m2、BFR、腰围、臀围、小腿围、IL-17水平升高是社区老年人肌少症的保护因素（P<0.05）。结论 上海市社区老年人肌少症患病率较高，肌少症的发生可能与年龄、锻炼、营养状况、衰弱、总胆固醇、IL-17和galectin-3水平相关。 |
| 英文摘要: |
| Objective To explore the prevalence of sarcopenia among elderly community residents in Shanghai and its related factors.Methods From July 2018 to July 2020,1 713 elderly residents from Zhoujiaqiao sub-district,Tianshan Road sub-district and Jiuting town in Shanghai were recruited by random sampling method.Their demographic data,anthropometric indices,and laboratory indicators were collected.According to the diagnostic criteria of sarcopenia,they were divided into sarcopenia group(n=354)and non-sarcopenia group(n=1 359).The influencing factors for sarcopenia were analyzed.Results The prevalence of sarcopenia among these subjects was 20.67%(354/1 713).Compared with the non-sarcopenia group,the sarcopenia group was older and had significantly lower body mass index(BMI),body fat rate(BFR),waist circumference,hip circumference,waist-to-hip ratio,mid-arm circumference,and calf circumference.They also had higher Fried frailty phenotype(FFP)score,lower mini-nutritional assessment(MNA)score,lower interleukin(IL)-17 level,and higher levels of total cholesterol,IL-6,tumor necrosis factor-alpha and galectin-3(all P＜0.05).Multiple Logistic regression analysis revealed that older age,BMI＜18.5 kg/m2,pre-frailty,frailty,and elevated levels of total cholesterol and galectin-3 were risk factors for sarcopenia in the elderly in the communities(P＜0.05),while exercise,BMI≥24.0 kg/m2,BFR,waist circumference,hip circumference,calf circumference and elevated IL-17 level were identified as protective factors(P＜0.05).Conclusion The prevalence of sarcopenia was relatively high among community-dwelling elderly residents in Shanghai.The occurrence of sarcopenia might be mainly related to age,exercise,nutritional status,frailty and the serum levels of total cholesterol,IL-17 and galectin-3. |
|
查看全文
查看/发表评论 下载PDF阅读器 |
| 关闭 |
|
|
|
